How can the philosophical and psychiatric theories of the subject help us to consider the place of the human being, his role, his interactions with the institution, or his involvement in the city? During the first year of this seminar, we tried to position the field of psychiatry between the medical and technical fields and the field of support and study with regard to the future of the subject. For this second year, we will try to better delineate its boundaries, to explore them and to identify the areas of strength and weakness, between biological reality and psychological reality. Does hallucination differ from perception of the world, do we consider psychiatry starting from the brain or the body, what is a psychological trauma, do biological determinism and psychological determinism exist? This seminar will help us to consider the relationship between psychiatry and the neurosciences as well as the social sciences and philosophy.